| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1301 | |
| Phytochemical name or plant extracts | 8-deoxygartanin | |
| PMID | 24555285 | |
| Literature evidence | Compounds 1-4 exhibited either significant o r moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines in vitro with IC50 values from 4.0 +/- 0.3 to 23.6+/- 1.5 microM by MTT colorimetric assay. | |
| IUPAC name | 1,3,5-trihydroxy-2,4-bis(3-methylbut-2-enyl)xanthen-9-one | |
| Phytochemicals’ class or type of plant extracts | Xanthone | |
| Source of phytochemicals or plant Extracts | Garcinia mangostana | |
| Geographical availability | Borneo, Malaya | |
| Plant parts | Pericarp, Stem | |
| Other cancers | Breast cancer, Liver cancer, Lung cancer, Nasopharyngeal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 16.8 ± 1.4 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, A549, Hep-G2, CNE and HT-29 | |
| Additional information | Inhibits p65 activation in HT-29 cell line | |
| PubChem ID | 392450 | |
| Additional PMIDs | 19839614 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:428073-1 | |
| Safety | NA |