| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-985 | |
| Phytochemical name or plant extracts | 8,8′-Oxo-biplumbagin | |
| PMID | 28933383 | |
| Literature evidence | As part of our search for natural products having antioxidant and anticancer properties, the phytochemical investigation of Diospyros shimbaensis (Ebenaceae), a plant belonging to a genus widely used in East African traditional medicine, was carried out. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Naphthoquinone | |
| Source of phytochemicals or plant Extracts | Diospyros shimbaensis | |
| Geographical availability | Kenya, Tanzania | |
| Plant parts | Stem and Root | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | EC50 = >25µM | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | From its stem and root barks the new naphthoquinone 8,8'-oxo-biplumbagin (1) was isolated. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:935986-1 | |
| Safety | NA |