Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1599 | |
Phytochemical name or plant extracts | 7-octenoic acid | |
PMID | 33333817 | |
Literature evidence | This study identified 10 candidate compounds that may have potential in the field of anticancer substances. | |
IUPAC name | oct-7-enoic acid | |
Phytochemicals’ class or type of plant extracts | Fatty acid | |
Source of phytochemicals or plant Extracts | Moringa oleifera | |
Geographical availability | India, Pakistan | |
Plant parts | Leaves | |
Other cancers | Breast cancer | |
Target gene or protein | Bcl-2 | |
Gene or Protein evidence | Three of identified compounds (7-octenoic acid, oleamide, and 1-phenyl-2-pentanol) showed anticancer activities by inducing cell cycle arrest and triggering apoptosis through suppressed Bcl-2 expression which subsequently promotes activation of caspase 3, indicators for the apoptosis pathway. | |
Target pathways | NA | |
IC50 | NA | |
Potency | NA | |
Cell line/ mice model | MDA-MB-231 | |
Additional information | NA | |
PubChem ID | 543977 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:584736-1 | |
Safety | NA |