| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1960 | |
| Phytochemical name or plant extracts | 7-acetylaltholactone | |
| PMID | 24868866 | |
| Literature evidence | The discovery of 3-deoxycardiobutanolide (2) from the fruits of this plant revealed that G. macrocalyx could be a valuable natural resource to obtain this compound as it has been previously reported to have a significant cytotoxicity against different cancer cell lines, especially HL-60 cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Styryllactone | |
| Source of phytochemicals or plant Extracts | Goniothalamus macrocalyx Ban | |
| Geographical availability | Vietnam | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer, Liver cancer, Squamous cell cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 60.2 µM against MCF-7 | |
| Potency | Compound 7 (7-acetylaltholactone) showed significant cytotoxicity against KB, HepG2, Lu and MCF7 cell lines with IC50 values of 13.1, 23.7, 26.3 and 60.2 µM, respectively. | |
| Cell line/ mice model | KB, HepG2, Lu, MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77070643-1 | |
| Safety | NA |