| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1454 | |
| Phytochemical name or plant extracts | 7',8'-Dihydroobolactone | |
| PMID | 33207963 | |
| Literature evidence | Compounds 4 and 6 showed significant cytotoxicity against A549, HCT-116, MDA-MB-231, PC-3 and HeLa with IC50 values from 2.25 to 8.97 µM. | |
| IUPAC name | (2R)-2-[[(2R)-6-oxo-2,3-dihydropyran-2-yl]methyl]-6-(2-phenylethyl)-2,3-dihydropyran-4-one | |
| Phytochemicals’ class or type of plant extracts | Pyranone | |
| Source of phytochemicals or plant Extracts | Cryptocarya yunnanensis | |
| Geographical availability | China South-Central | |
| Plant parts | Leaves and twigs | |
| Other cancers | Breast cancer, Prostate cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 2.64+-0.09 µM against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | HCT-116, MDA-MB-231, PC-3 | |
| Additional information | Displays good cytotoxicity against HCT-116, MDA-MB-231 and PC-3 | |
| PubChem ID | 46911676 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:316944-2 | |
| Safety | NA |