| Properties | Information |
|---|---|
| PhytoCAT-ID | PhytoCAT-1559 |
| Phytochemical name or plant extracts | 6-Prenylchrysin |
| PMID | 15930306 |
| Literature evidence | Whereas GF120918 strongly inhibited the ATPase activity of wild-type ABCG2, neither 6-prenylchrysin nor tectochrysin altered the activity. |
| IUPAC name | 5,7-dihydroxy-6-(3-methylbut-2-enyl)-2-phenylchromen-4-one |
| Phytochemicals’ class or type of plant extracts | Flavonoid |
| Source of phytochemicals or plant Extracts | NA |
| Geographical availability | NA |
| Plant parts | NA |
| Other cancers | Breast cancer |
| Target gene or protein | ABCG2 |
| Gene or Protein evidence | Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2. |
| Target pathways | NA |
| IC50 | NA |
| Potency | NA |
| Cell line/ mice model | HEK-293, MDA-MB-231 |
| Additional information | NA |
| PubChem ID | 443123 |
| Additional PMIDs | NA |
| Additional sources of information | NA |
| Safety | NA |