Phytochemical Name : 6,8-diprenylnarigenin (6,8-diPN)

Properties Information
PhytoCAT-ID PhytoCAT-1840
Phytochemical name or plant extracts 6,8-diprenylnarigenin (6,8-diPN)
PMID 25044854
Literature evidence METHODS AND RESULTS: ABCG2-inhibitory activity of xanthohumol (XN), isoxanthohumol (IX), 6-prenylnaringenin (6-PN), 8-prenylnaringenin (8-PN), and 6,8-diprenylnarigenin (6,8-diPN) was evaluated using mitoxantrone accumulation and vesicular transport assays.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Humulus lupulus
Geographical availability Alberta, Connecticut, Delaware, Illinois, Indiana, Iowa, Kansas, Kentucky, Maine, Manitoba, Maryland, Massachusetts, Michigan, Minnesota, Montana, Nebraska, New Brunswick, New Hampshire, New Jersey, New York, Newfoundland, North Dakota, Nova Scotia, Ohio, Ontario, Pennsylvania, Prince Edward I., Québec, Rhode I., Saskatchewan, South Dakota, Vermont, Virginia, West Virginia, Wisconsin
Plant parts NA
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency NA
Cell line/ mice model MDA-MB-231
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:854179-1
Safety NA