| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-400 | |
| Phytochemical name or plant extracts | 6,7-dehydroroyleanone (3) | |
| PMID | 29451710 | |
| Literature evidence | The individual compounds (1, 3Â -Â 8) were screened for cytotoxic activity, using the sulforhodamine B bioassay (SRB) method. | |
| IUPAC name | (4bS,8aS)-1-hydroxy-4b,8,8-trimethyl-2-propan-2-yl-5,6,7,8a-tetrahydrophenanthrene-3,4-dione | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Salvia deserta | |
| Geographical availability | Altay, Kazakhstan, Kirgizstan, Tadzhikistan, Uzbekistan, West Siberia, Xinjiang | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 13.320±1.473 μM against MDA-MB-231 20.779±1.257 μM against MCF-7 | |
| Potency | As the results, Compounds 3, 5, and 8 showed cytotoxic potency against A549, MDA-MB-231, KB, KB-VIN, and MCF7 cell lines with IC50 values ranging from 6.5 to 10.2 μm. | |
| Cell line/ mice model | A549, MDA-MB-231, KB, KB-VIN, and MCF-7 | |
| Additional information | NA | |
| PubChem ID | 2751794 | |
| Additional PMIDs | 24451247 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:456094-1 | |
| Safety | NA |