| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2050 | |
| Phytochemical name or plant extracts | 6''-O-Acetylsaikosaponin A | |
| PMID | 26259802 | |
| Literature evidence | Among them, compound 20 was isolated from the natural product for the first time. | |
| IUPAC name | [(2R,3S,4S,5R,6S)-6-[(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-[[(1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-10-yl]oxy]-6-methyloxan-4-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Bupleurum chinense | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Inner Mongolia, Korea, Manchuria, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Liver cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 36.22 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | A549, HepG2, Hep3B, BCap-37, MCF-7 | |
| Additional information | Specially, compounds 1, 3–4, 6–9, 11–13, 16–18 and 20 possessed a much higher cytotoxic effect against the HepG2 cell line than 5-fluorouracil. Compound 13 is 6''-O-acetylsaikosaponin A | |
| PubChem ID | 21637629 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:839099-1 | |
| Safety | NA |