| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1235 | |
| Phytochemical name or plant extracts | 5-methoxy-(E)-resveratrol 3-O-rutinoside | |
| PMID | 30346066 | |
| Literature evidence | In addition, compounds 1-3 showed low toxicity against normal human prostate cell line, with selectivity indices greater than five across the carcinoma cells, indicating that the compounds possess potential in the development of low-toxicity chemotherapeutic agents. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Resveratrol derivative | |
| Source of phytochemicals or plant Extracts | Commiphora africana | |
| Geographical availability | Angola, Benin, Botswana, Burkina, Cameroon, Caprivi Strip, Chad, Djibouti, Eritrea, Ethiopia, Gambia, Ghana, Ivory Coast, Kenya, KwaZulu-Natal, Malawi, Mali, Mauritania, Mozambique, Namibia, Niger, Nigeria, Northern Provinces, Rwanda, Senegal, Somalia, Sudan, Swaziland, Tanzania, Togo, Uganda, Zambia, Zaïre, Zimbabwe | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Prostate cancer, Lung cancer, Liver cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 16.80 ± 0.51 µg/ml against MCF-7 | |
| Potency | In this study, we report the antiproliferative potentials of the extracts and isolated compounds of C. africana on four human carcinoma cells. These results validate the folklore use of C. africana in the treatment of cancer. | |
| Cell line/ mice model | MCF-7, A549, PC3, HepG2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:127576-1 | |
| Safety | NA |