| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-718 | |
| Phytochemical name or plant extracts | 5-((8Z, 11Z, 14Z)-hexatriaconta-8, 11, 14-trienyl) benzene-1,3-diol | |
| PMID | 28222398 | |
| Literature evidence | Results of this study suggest that isolated new resorcinolic lipid can induce apoptosis in MCF-7 cells, possibly via oxidative stress mechanism. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Resorcinolic lipid | |
| Source of phytochemicals or plant Extracts | Mangifera zeylanica | |
| Geographical availability | Sri Lanka | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | Caspase 7 | |
| Gene or Protein evidence | Treatment with compound 1 led to an increase in caspase 7 activity, morphological features of apoptosis and DNA fragmentation in MCF-7 cells. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Furthermore, it also led to an increase in ROS and GST levels while depleting GSH levels. Results of this study suggest that isolated new resorcinolic lipid can induce apoptosis in MCF-7 cells, possibly via oxidative stress mechanism. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:69987-1 | |
| Safety | NA |