| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-543 | |
| Phytochemical name or plant extracts | 5,6-anhydrohupehenine | |
| PMID | 34653443 | |
| Literature evidence | These results suggest that 5,6-anhydrohupehenine is a promising compound to be designed as novel cytotoxic agents. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Fritillaria hupehensis | |
| Geographical availability | China South-Central, China Southeast | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 22.05 μM against MCF-7 | |
| Potency | These results suggest that 5,6-anhydrohupehenine is a promising compound to be designed as novel cytotoxic agents. | |
| Cell line/ mice model | MCF-7, HepG2 | |
| Additional information | The cytotoxicity evaluation of all 5,6-anhydrohupehenine derivatives against HepG2 and MCF-7 human cancer cells revealed that 9s displayed best activity against HepG2 cells with IC50 at 1.27 μM. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:535164-1 | |
| Safety | NA |