Phytochemical Name : 4beta,14-dihydro-3-dehydrozaluzanin C

Properties Information
PhytoCAT-ID PhytoCAT-159
Phytochemical name or plant extracts 4beta,14-dihydro-3-dehydrozaluzanin C
PMID 24689209
Literature evidence The chloroform extracts of the root, which displayed antiproliferative effect against human tumor cell lines, was subjected to bioactivity-guided multistep chromatographic separation.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Sesquiterpene lactone
Source of phytochemicals or plant Extracts Onopordum acanthium
Geographical availability Afghanistan, Albania, Algeria, Altay, Austria, Baltic States, Belarus, Belgium, Bulgaria, Central European Rus, Corse, Czechoslovakia, Denmark, East European Russia, France, Germany, Greece, Hungary, Iran, Iraq, Italy, Kazakhstan, Kirgizstan, Krym, Netherlands, North Caucasus, Northwest European R, Norway, Pakistan, Portugal, Romania, Saudi Arabia, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan, Ukraine, Uzbekistan, West Himalaya, Xinjiang, Yemen, Yugoslavia
Plant parts Root
Other cancers Breast cancer, Cervical cancer, Skin cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 2.7-15.1 µM against MCF-7
Potency NA
Cell line/ mice model HeLa, MCF-7 , A431
Additional information  NA
PubChem ID NA
Additional PMIDs 24689209
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:235234-1
Safety NA