Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-159 | |
Phytochemical name or plant extracts | 4beta,14-dihydro-3-dehydrozaluzanin C | |
PMID | 24689209 | |
Literature evidence | The chloroform extracts of the root, which displayed antiproliferative effect against human tumor cell lines, was subjected to bioactivity-guided multistep chromatographic separation. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Sesquiterpene lactone | |
Source of phytochemicals or plant Extracts | Onopordum acanthium | |
Geographical availability | Afghanistan, Albania, Algeria, Altay, Austria, Baltic States, Belarus, Belgium, Bulgaria, Central European Rus, Corse, Czechoslovakia, Denmark, East European Russia, France, Germany, Greece, Hungary, Iran, Iraq, Italy, Kazakhstan, Kirgizstan, Krym, Netherlands, North Caucasus, Northwest European R, Norway, Pakistan, Portugal, Romania, Saudi Arabia, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan, Ukraine, Uzbekistan, West Himalaya, Xinjiang, Yemen, Yugoslavia | |
Plant parts | Root | |
Other cancers | Breast cancer, Cervical cancer, Skin cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 2.7-15.1 µM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | HeLa, MCF-7 , A431 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | 24689209 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:235234-1 | |
Safety | NA |