| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-56 | |
| Phytochemical name or plant extracts | 4'-O-methyl-8-prenylnaringenin | |
| PMID | 24443427 | |
| Literature evidence | In addition, evaluation of their cytotoxic activities against HL60, A549, AZ521, and SK-BR-3 human cancer cell lines, isoazadironolide (1), 4'-O-methyl-8-prenylnaringenin (5), euchrestaflavanone A (8), 9, and 3-methoxy-3'-prenylnaringenin (12) revealed potent cytotoxicities against one or more cell lines with IC50 values in the range of 4.5-9.9 μM. | |
| IUPAC name | (2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Azadirachta indica | |
| Geographical availability | Assam, Bangladesh, Cambodia, Laos, Myanmar, Thailand, Vietnam | |
| Plant parts | Flowers | |
| Other cancers | Breast cancer, Gastric cancer, Lung cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 7.9±1.2 μM against SKBR-3 | |
| Potency | In addition, evaluation of their cytotoxic activities against HL60, A549, AZ521, and SK-BR-3 human cancer cell lines, isoazadironolide (1), 4'-O-methyl-8-prenylnaringenin (5), euchrestaflavanone A (8), 9, and 3-methoxy-3'-prenylnaringenin (12) revealed potent cytotoxicities against one or more cell lines with IC50 values in the range of 4.5-9.9 μM. | |
| Cell line/ mice model | HL60, A549, AZ521, SKBR-3 | |
| Additional information | NA | |
| PubChem ID | 45272659 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:1213180-2 | |
| Safety | NA |