| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1169 | |
| Phytochemical name or plant extracts | 3beta-trans-p-coumaroyloxy-2alpha-hydroxyolean-12-en-28-oic acid | |
| PMID | 17488026 | |
| Literature evidence | Among the compounds isolated, 2alpha-hydroxyursolic acid, 2alpha-hydroxy-3beta-{[(2E)-3-phenyl-1-oxo-2-propenyl]oxy}olean-12-en-28-oic acid, and 3beta-trans-p-coumaroyloxy-2alpha-hydroxyolean-12-en-28-oic acid showed higher antiproliferative activity toward HepG2 cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Psidium guajava | |
| Geographical availability | Argentina Northeast, Argentina Northwest, Bolivia, Brazil Northeast, Brazil South, Brazil Southeast, Brazil West-Central, Colombia, Ecuador, Paraguay, Peru, Venezuela | |
| Plant parts | Peels | |
| Other cancers | Breast cancer, Liver cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Here we reported triterpenoids isolated from apple peels had potent antiproliferative activity against HepG2 human liver cancer cells, Caco-2 human colon cancer cells, and MCF-7 human breast cancer cells. | |
| Cell line/ mice model | MCF-7, HepG2, Caco-2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:600841-1 | |
| Safety | NA |