| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1297 | |
| Phytochemical name or plant extracts | 3-O-trans-p-coumaroylmaslinic acid | |
| PMID | 23479388 | |
| Literature evidence | Most of these compounds showed significant cytotoxic activities against four human cancer cell lines (A549, HCT116, MDA-MB-231, and CCRF-CEM), and the structure-activity relationships are also discussed. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Prinsepia utilis Royle | |
| Geographical availability | Assam, China South-Central, East Himalaya, India, Myanmar, Nepal, Pakistan, Tibet, West Himalaya | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Lung cancer, Colon cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 12.4 ± 1.1 µM against MDA-MB-231 | |
| Potency | It was found that compounds 7 and 8 showed potent cytotoxicity against A549, HCT116, MDA?MB?231, and CCRF?CEM cell lines [IC50 : 7.1, 2.8, 12.4, and 4.3 µM, and IC50 : 9.7, 10.2, 15.3, and 3.7 µM, respectively]. | |
| Cell line/ mice model | A549, HCT116, MDA-MB-231, CCRF-CEM | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:729396-1 | |
| Safety | NA |