Properties |
Information |
PhytoCAT-ID |
PhytoCAT-1294 |
Phytochemical name or plant extracts |
3-O-cis-p-coumaroyltormentic acid |
PMID |
23479388 |
Literature evidence |
Most of these compounds showed significant cytotoxic activities against four human cancer cell lines (A549, HCT116, MDA-MB-231, and CCRF-CEM), and the structure-activity relationships are also discussed. |
IUPAC name |
(1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,11-dihydroxy-10-[(Z)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
Phytochemicals’ class or type of plant extracts |
Triterpenoid |
Source of phytochemicals or plant Extracts |
Prinsepia utilis Royle |
|
Geographical availability |
Assam, China South-Central, East Himalaya, India, Myanmar, Nepal, Pakistan, Tibet, West Himalaya |
Plant parts |
Aerial parts |
Other cancers |
Breast cancer, Lung cancer, Colon cancer, Leukemia |
Target gene or protein |
NA |
Gene or Protein evidence |
NA |
Target pathways |
NA |
IC50 |
16.2 ± 1.1 µM against MDA-MB-231 |
Potency |
Most of these compounds showed significant cytotoxic activities against four human cancer cell lines (A549, HCT116, MDA-MB-231, and CCRF-CEM), and the structure-activity relationships are also discussed. |
Cell line/ mice model |
A549, HCT116, MDA-MB-231, CCRF-CEM |
Additional information |
NA |
PubChem ID |
14335956 |
Additional PMIDs |
NA |
Additional sources of information |
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:729396-1 |
Safety |
NA |