Phytochemical Name : 3-O-cis-p-coumaroyltormentic acid

Properties Information
PhytoCAT-ID PhytoCAT-1294
Phytochemical name or plant extracts 3-O-cis-p-coumaroyltormentic acid
PMID 23479388
Literature evidence Most of these compounds showed significant cytotoxic activities against four human cancer cell lines (A549, HCT116, MDA-MB-231, and CCRF-CEM), and the structure-activity relationships are also discussed.
IUPAC name (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,11-dihydroxy-10-[(Z)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
Phytochemicals’ class or type of plant extracts Triterpenoid
Source of phytochemicals or plant Extracts Prinsepia utilis Royle
Geographical availability Assam, China South-Central, East Himalaya, India, Myanmar, Nepal, Pakistan, Tibet, West Himalaya
Plant parts Aerial parts
Other cancers Breast cancer, Lung cancer, Colon cancer, Leukemia
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 16.2 ± 1.1 µM against MDA-MB-231
Potency Most of these compounds showed significant cytotoxic activities against four human cancer cell lines (A549, HCT116, MDA-MB-231, and CCRF-CEM), and the structure-activity relationships are also discussed.
Cell line/ mice model A549, HCT116, MDA-MB-231, CCRF-CEM
Additional information  NA
PubChem ID 14335956
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:729396-1
Safety NA