Phytochemical Name : 3β,13β-dihydroxy-12,13-dihydroursolic acid (7)

Properties Information
PhytoCAT-ID PhytoCAT-227
Phytochemical name or plant extracts 3β,13β-dihydroxy-12,13-dihydroursolic acid (7)
PMID 27359376
Literature evidence The novel triterpenoids were elucidated to be 3β,13β-dihydroxy-12,13-dihydrooleanolic acid (1), 3β,12β,13β-trihydroxy-12,13-dihydrooleanolic acid (2, TOA), and 3β,13β-dihydroxy-12,13-dihydroursolic acid (7), respectively.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Triterpenoid
Source of phytochemicals or plant Extracts Vitis vinifera
Geographical availability Albania, Austria, Bulgaria, Corse, Cyprus, Czechoslovakia, France, Germany, Greece, Hungary, Iran, Iraq, Italy, Kirgizstan, Krym, Lebanon-Syria, North Caucasus, Palestine, Romania, Sardegna, Sicilia, Switzerland, Tadzhikistan, Transcaucasus, Turkey, Turkey-in-Europe, Turkmenistan, Ukraine, Uzbekistan, Yugoslavia
Plant parts Fruits
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency Compounds 1, 3 and 7 also exhibited potent antiproliferative activity against MCF-7/DOX cells, with an EC50 value of 7.10 ± 0.65, 10.22 ± 0.90 and 8.91 ± 1.12 μM.
Cell line/ mice model MCF-7/DOX
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30478388-3
Safety NA