Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-227 | |
Phytochemical name or plant extracts | 3β,13β-dihydroxy-12,13-dihydroursolic acid (7) | |
PMID | 27359376 | |
Literature evidence | The novel triterpenoids were elucidated to be 3β,13β-dihydroxy-12,13-dihydrooleanolic acid (1), 3β,12β,13β-trihydroxy-12,13-dihydrooleanolic acid (2, TOA), and 3β,13β-dihydroxy-12,13-dihydroursolic acid (7), respectively. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Triterpenoid | |
Source of phytochemicals or plant Extracts | Vitis vinifera | |
Geographical availability | Albania, Austria, Bulgaria, Corse, Cyprus, Czechoslovakia, France, Germany, Greece, Hungary, Iran, Iraq, Italy, Kirgizstan, Krym, Lebanon-Syria, North Caucasus, Palestine, Romania, Sardegna, Sicilia, Switzerland, Tadzhikistan, Transcaucasus, Turkey, Turkey-in-Europe, Turkmenistan, Ukraine, Uzbekistan, Yugoslavia | |
Plant parts | Fruits | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | Compounds 1, 3 and 7 also exhibited potent antiproliferative activity against MCF-7/DOX cells, with an EC50 value of 7.10 ± 0.65, 10.22 ± 0.90 and 8.91 ± 1.12 μM. | |
Cell line/ mice model | MCF-7/DOX | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30478388-3 | |
Safety | NA |