Properties |
Information |
PhytoCAT-ID |
PhytoCAT-224 |
Phytochemical name or plant extracts |
3β,13β-dihydroxy-12,13-dihydrooleanolic acid (1) |
PMID |
27359376 |
Literature evidence |
The novel triterpenoids were elucidated to be 3β,13β-dihydroxy-12,13-dihydrooleanolic acid (1), 3β,12β,13β-trihydroxy-12,13-dihydrooleanolic acid (2, TOA), and 3β,13β-dihydroxy-12,13-dihydroursolic acid (7), respectively. |
IUPAC name |
NA |
Phytochemicals’ class or type of plant extracts |
Triterpenoid |
Source of phytochemicals or plant Extracts |
Vitis vinifera |
|
Geographical availability |
Albania, Austria, Bulgaria, Corse, Cyprus, Czechoslovakia, France, Germany, Greece, Hungary, Iran, Iraq, Italy, Kirgizstan, Krym, Lebanon-Syria, North Caucasus, Palestine, Romania, Sardegna, Sicilia, Switzerland, Tadzhikistan, Transcaucasus, Turkey, Turkey-in-Europe, Turkmenistan, Ukraine, Uzbekistan, Yugoslavia |
Plant parts |
Fruits |
Other cancers |
Breast cancer |
Target gene or protein |
NA |
Gene or Protein evidence |
NA |
Target pathways |
NA |
IC50 |
NA |
Potency |
Compounds 1, 3 and 7 also exhibited potent antiproliferative activity against MCF-7/DOX cells, with an EC50 value of 7.10 ± 0.65, 10.22 ± 0.90 and 8.91 ± 1.12 μM. |
Cell line/ mice model |
MCF-7/DOX |
Additional information |
Compounds 1 and 2 also exhibited potent antioxidant activities. |
PubChem ID |
NA |
Additional PMIDs |
NA |
Additional sources of information |
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30478388-2 |
Safety |
NA |