Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1567 | |
Phytochemical name or plant extracts | 3,5,7,3',4'-pentahydroxyflavonol-3-O-beta-D-glucopyranoside | |
PMID | 16968064 | |
Literature evidence | Ursolic acid, quercetin, and 3,5,7,3',4'-pentahydroxyflavonol-3-O-beta-D-glucopyranoside showed potent inhibitory activity toward the proliferation of MCF-7 cells, with EC50 values of 11.7 +/- 0.1, 137.5 +/- 2.6, and 23.9 +/- 3.9 microM, respectively. | |
IUPAC name | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2H-chromen-4-one | |
Phytochemicals’ class or type of plant extracts | Flavonoid | |
Source of phytochemicals or plant Extracts | Cranberry | |
Geographical availability | NA | |
Plant parts | NA | |
Other cancers | Breast cancer, Liver cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | EC50 = 23.9 +/- 3.9 microM against MCF-7 | |
Cell line/ mice model | HepG2, MCF-7 | |
Additional information | These results showed cranberry phytochemical extracts have potent antioxidant and antiproliferative activities. | |
PubChem ID | 18392041 | |
Additional PMIDs | NA | |
Additional sources of information | NA | |
Safety | NA |