Phytochemical Name : 3,5,7,3',4'-pentahydroxyflavonol-3-O-beta-D-glucopyranoside

Properties Information
PhytoCAT-ID PhytoCAT-1567
Phytochemical name or plant extracts 3,5,7,3',4'-pentahydroxyflavonol-3-O-beta-D-glucopyranoside
PMID 16968064
Literature evidence Ursolic acid, quercetin, and 3,5,7,3',4'-pentahydroxyflavonol-3-O-beta-D-glucopyranoside showed potent inhibitory activity toward the proliferation of MCF-7 cells, with EC50 values of 11.7 +/- 0.1, 137.5 +/- 2.6, and 23.9 +/- 3.9 microM, respectively.
IUPAC name 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2H-chromen-4-one
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Cranberry
Geographical availability NA
Plant parts NA
Other cancers Breast cancer, Liver cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency EC50 = 23.9 +/- 3.9 microM against MCF-7
Cell line/ mice model HepG2, MCF-7
Additional information  These results showed cranberry phytochemical extracts have potent antioxidant and antiproliferative activities.
PubChem ID 18392041
Additional PMIDs NA
Additional sources of information NA
Safety NA