| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-761 | |
| Phytochemical name or plant extracts | 3,10,11-trimethoxy-1,2-methylenedioxy-7-oxoaporphine | |
| PMID | 33722552 | |
| Literature evidence | The isolated compounds were subjected to evaluate cytotoxic activities in vitro, compound 1 had activity against HL-60 and HELA (IC50 value of 8.4 μM and 5.2 μM, respectively), compound 2 against MCF-7 (IC50 value of 3.7 μM), compound 3 against HEPG2 (IC50 value of 10.8 μM), respectively. | |
| IUPAC name | 7,17,18-trimethoxy-3,5-dioxa-11-azapentacyclo[10.7.1.0²,⁶.0⁸,²⁰.0¹⁴,¹⁹]icosa-1(20),2(6),7,9,11,14(19),15,17-octaen-13-one | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Fissistigma oldhamii | |
| Geographical availability | China South-Central, China Southeast, Hainan, Taiwan | |
| Plant parts | Stem | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 3.7 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:73046-1 | |
| Safety | NA |