| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1833 | |
| Phytochemical name or plant extracts | 28-hydroxy-20-oxo-30-norlupane-3β-palmitate | |
| PMID | 24975046 | |
| Literature evidence | Compound 1-3 exhibited the significant cytotoxic activities with low IC50 values (IC50 < 4.0 μM) against six tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901, NCI-H460 and BGC-823). | |
| IUPAC name | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-icosahydro-1H-cyclopenta[a]chrysen-9-yl hexadecanoate | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Saussurea phyllocephala | |
| Geographical availability | China South-Central, Myanmar, Thailand | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer, Cervical cancer, Liver cancer, Stomach cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 2.5 μM against MCF-7 | |
| Potency | Compound 1-3 exhibited the significant cytotoxic activities with low IC50 values (IC50 < 4.0 μM) against six tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901, NCI-H460 and BGC-823). Compound 2 is 28-hydroxy-20-oxo-30-norlupane-3β-palmitate | |
| Cell line/ mice model | (MCF-7, HeLa, HepG2, SGC-7901, NCI-H460 and BGC-824 | |
| Additional information | Exhibits significant cytotoxic activities against six tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901, NCI-H460 and BGC-823) | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:242526-1 | |
| Safety | NA |