| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2058 | |
| Phytochemical name or plant extracts | 2-acetyl-7-methoxynaphtho[2,3-b]furan-4,9-quinone (AMNQ) | |
| PMID | 28887921 | |
| Literature evidence | AMNQ is a potential antiproliferative natural compound that deserves more investigations to develop novel cytotoxic drugs against sensitive and MDR cancers. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Quinone | |
| Source of phytochemicals or plant Extracts | Millettia versicolor | |
| Geographical availability | Angola, Cameroon, Congo, Gabon, Zaïre | |
| Plant parts | Bark | |
| Other cancers | Breast cancer, Liver cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 3.26 µM against MDA-MB231/BCRP breast cancer cells | |
| Potency | NA | |
| Cell line/ mice model | MDA-MB-231/BCRP, HepG2, CCRF-CEM | |
| Additional information | The results of this work demonstrate the cytotoxicity of AMNQ towards various types of cancer cell lines, including MDR phenotypes. AMNQ is a potential antiproliferative natural compound that deserves more investigations to develop novel cytotoxic drugs against sensitive and MDR cancers. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:507570-1 | |
| Safety | NA |