Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1844 | |
Phytochemical name or plant extracts | 2α,3β,28-trihydroxy-urs-20(30)-ene | |
PMID | 25088972 | |
Literature evidence | Among the triterpenoids isolated, 2α,3β,19α-trihydroxy-urs-12-en-28-oic acid (7), 9 and 10 showed high potent inhibitory activity toward the proliferation of HepG2 cells, which the IC50 values were lower than 5 μM. | |
IUPAC name | (2R,3R,6aR,6bR,8aS,12R,12bR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,12,14b-hexamethyl-11-methylidene-docosahydropicene-2,3-diol | |
Phytochemicals’ class or type of plant extracts | Triterpenoid | |
Source of phytochemicals or plant Extracts | Sour jujube | |
Geographical availability | NA | |
Plant parts | NA | |
Other cancers | Breast cancer, Liver cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 1.5 ± 0.1 μM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | HepG2, MCF-7 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | NA | |
Safety | NA |