| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-498 | |
| Phytochemical name or plant extracts | 2,4-di-tert-butylphenol (HU-2) | |
| PMID | 30475646 | |
| Literature evidence | HU-2 has potential for development as a novel anti-inflammatory and anticancer agent. | |
| IUPAC name | 2,4-ditert-butylphenol | |
| Phytochemicals’ class or type of plant extracts | NA | |
| Source of phytochemicals or plant Extracts | Humboldtia unijuga | |
| Geographical availability | India | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Skin cancer | |
| Target gene or protein | p53 | |
| Gene or Protein evidence | HU-2 showed a superior dose dependent anticancer effect through activation of p53 gene over HU-1 in MCF-7 cells. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | HU-2 has potential for development as a novel anti-inflammatory and anticancer agent. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | 7311 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:498715-1 | |
| Safety | NA |