| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-849 | |
| Phytochemical name or plant extracts | 2,3-seco-taraxer-14-en-2,3-lactone (pycanocarpine) | |
| PMID | 24658565 | |
| Literature evidence | Ursolic acid (1) displayed potent cytotoxic activity against HeLa, HT-29 and MCF-7 cells with IC₅₀ values of 10, 10 and 20 µM respectively. | |
| IUPAC name | (1R,5R,10R,11S,14R,15R,21R)-1,5,8,8,11,15,20,20-octamethyl-18-oxapentacyclo[12.9.0.02,11.05,10.015,21]tricos-2-en-17-one | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Pleiocarpa pycnantha | |
| Geographical availability | Angola, Benin, Burundi, Cabinda, Cameroon, Central African Repu, Congo, Gabon, Ghana, Guinea-Bissau, Kenya, Mozambique, Nigeria, Rwanda, Senegal, Sudan, Tanzania, Togo, Uganda, Zambia, Zaïre, Zimbabwe | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 20 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | 102236073 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:81144-1 | |
| Safety | NA |