Properties |
Information |
PhytoCAT-ID |
PhytoCAT-501 |
Phytochemical name or plant extracts |
2,3,9-Trimethoxypterocarpan |
PMID |
24952350 |
Literature evidence |
Pterocarpans, a family of isoflavonoids found in the diverse Fabaceae, display potent cytotoxic activity over a panel of tumor cell lines, and among those tested, 2,3,9- trimethoxypterocarpan displays the most potent activity. |
IUPAC name |
2,3,9-trimethoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene |
Phytochemicals’ class or type of plant extracts |
Flavonoid |
Source of phytochemicals or plant Extracts |
Pisum sativum |
|
Geographical availability |
Afghanistan, Albania, Algeria, Bulgaria, Corse, Cyprus, Egypt, France, Greece, Iran, Iraq, Italy, Krym, Lebanon-Syria, Libya, Morocco, North Caucasus, Palestine, Portugal, Romania, Sardegna, Sicilia, Spain, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Turkmenistan, Ukraine, Yugoslavia |
Plant parts |
NA |
Other cancers |
Breast cancer |
Target gene or protein |
NA |
Gene or Protein evidence |
NA |
Target pathways |
NA |
IC50 |
NA |
Potency |
Pterocarpans, a family of isoflavonoids found in the diverse Fabaceae, display potent cytotoxic activity over a panel of tumor cell lines, and among those tested, 2,3,9- trimethoxypterocarpan displays the most potent activity. |
Cell line/ mice model |
MCF-7, T47D, HS578T |
Additional information |
NA |
PubChem ID |
11151159 |
Additional PMIDs |
NA |
Additional sources of information |
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:501912-1 |
Safety |
NA |