| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-435 | |
| Phytochemical name or plant extracts | 2',4'-dihydroxy-6'-methoxychalcone | |
| PMID | 30389223 | |
| Literature evidence | Cell cycle and mitochondrial membrane potential (MMP) were all analyzed via flow cytometry meanwhile levels of reactive oxygen species (ROS) was measured by spectrophotometry. | |
| IUPAC name | 3-(2,4-dihydroxy-6-methoxyphenyl)-1-phenylprop-2-en-1-one | |
| Phytochemicals’ class or type of plant extracts | Chalcone | |
| Source of phytochemicals or plant Extracts | Erythrina abyssinica | |
| Geographical availability | Angola, Botswana, Burundi, Central African Repu, Eritrea, Ethiopia, Kenya, Malawi, Mozambique, Rwanda, Sudan, Tanzania, Uganda, Zambia, Zaïre, Zimbabwe | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 6.30 μM against MCF-7 | |
| Potency | Compounds 1 induced apoptosis in MCF-7 cells mediated by increase ROS production and MMP loss. | |
| Cell line/ mice model | MCF-7, A549 | |
| Additional information | NA | |
| PubChem ID | 67218246 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:494336-1 | |
| Safety | NA |