| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1464 | |
| Phytochemical name or plant extracts | 15-hydroxydehydroabietic acid | |
| PMID | 26969787 | |
| Literature evidence | The antimicrobial activities against Staphylococcus aureus, Escherichia coli and Monilia albicans of all compounds were also tested, but none of them showed significant activities. | |
| IUPAC name | (1R,4aS,10aR)-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Abies fargesii | |
| Geographical availability | China North-Central, China South-Central | |
| Plant parts | Leaves and branches | |
| Other cancers | Breast cancer, Skin cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 42.8 µM against MCF-7 | |
| Potency | Only compounds 5 and 12 exhibited weak anti-proliferative effects against three cancer cell lines (B16, MCF7, and HepG2) with IC50 values range from 14.8 to 42.8 ?M. Compound 12 is 15-hydroxydehydroabietic acid. | |
| Cell line/ mice model | B16, MCF-7, and HepG2 | |
| Additional information | Exhibits weak anti-proliferative effects against three cancer cell lines (B16, MCF7, and HepG2) | |
| PubChem ID | 14487943 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:261522-1 | |
| Safety | Irritant, as given in pubchem |