Phytochemical Name : 12α-acetoxy-7-deacetylazadirone

Properties Information
PhytoCAT-ID PhytoCAT-594
Phytochemical name or plant extracts 12α-acetoxy-7-deacetylazadirone
PMID 26320684
Literature evidence The antiplasmodial activities of the crude extracts and the isolated constituents against the D6 and W2 strains of Plasmodium falciparum were determined using the semiautomated micro dilution technique that measures the ability of the extracts to inhibit the incorporation of (G-(3)H, where G is guanine) hypoxanthine into the malaria parasite.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Triterpenoid
Source of phytochemicals or plant Extracts Turraea nilotica Turraea robusta
Geographical availability Turraea nilotica - Burundi, Ethiopia, Kenya, Malawi, Mozambique, Northern Provinces, Somalia, Sudan, Swaziland, Tanzania, Zambia, Zimbabwe Turraea robusta - Cameroon, Kenya, Malawi, Tanzania, Uganda, Zambia, Zaïre
Plant parts Root Stem
Other cancers Breast cancer, Larynx cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 104.6±7.1 µg/mL against 4T1
Potency NA
Cell line/ mice model 4T1, HEp2, Vero
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579805-1 https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579836-1
Safety NA