| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-392 | |
| Phytochemical name or plant extracts | 1,8-cineole | |
| PMID | 29034738 | |
| Literature evidence | The essential oil of the sample investigated in this study which was a 1,8-cineole chemotype and 1,8-cineole showed moderate antimicrobial activity and significantly inhibited the activity of acetylcholinesterase enzyme. | |
| IUPAC name | 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane | |
| Phytochemicals’ class or type of plant extracts | Monoterpenoid | |
| Source of phytochemicals or plant Extracts | Nepeta menthoides | |
| Geographical availability | Iran, Iraq | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Ovarian cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 1.231 μL/mL against MCF-7 2.727 μL/mL against T47D 2.130 μL/mL against MDA-MB-231 | |
| Potency | Cytotoxicity evaluation against three breast cancer cell lines showed a potent inhibitory activity. | |
| Cell line/ mice model | MCF-7, T47D, MDA-MB-231, A2780 | |
| Additional information | The essential oil of 1,8-cineole chemotype and 1,8-cineole showed significant antimicrobial, acetylcholinesterase inhibitory and cytotoxic activities | |
| PubChem ID | 2758 | |
| Additional PMIDs | 32235558 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:452579-1 | |
| Safety | NA |