| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1006 | |
| Phytochemical name or plant extracts | Julibroside (J29) | |
| PMID | 16504508 | |
| Literature evidence | Compounds 1, 2, and 3 displayed significant anti-tumor activities in vitro against PC-3M-1E8, HeLa, and MDA-MB-435 cancer cell lines at 10microM assayed by SRB and MTT methods. | |
| IUPAC name | [(2S,3R,4S,5S,6R)-3-[(2S,3R,4S,5S,6S)-5-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxy-6-methyl-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] (3S,4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3-acetamido-6-[[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxymethyl]-4,5-dihydroxyoxan-2-yl]oxy-5-hydroxy-3-[(2E,6R)-2-(hydroxymethyl)-6-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyocta-2,7-dienoyl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid saponin | |
| Source of phytochemicals or plant Extracts | Albizia julibrissin | |
| Geographical availability | Assam, Bangladesh, China North-Central, China South-Central, China Southeast, East Himalaya, India, Iran, Japan, Korea, Myanmar, Nansei-shoto, Nepal, Pakistan, Taiwan, Tibet, Transcaucasus, West Himalaya | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Cervical cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Julibroside J29 (1), julibroside J30 (2), and julibroside J31 (3) showed marked inhibitory activities against PC-3M1E8, MDA-MB-435, and HeLa cancer cell lines in vitro at 10 lM assayed by SRB and MTT methods | |
| Cell line/ mice model | MDA-MB-435, PC-3M-1E8, HeLa | |
| Additional information | Displays significant anti-tumor activities in vitro against PC-3M-1E8, HeLa, and MDA-MB-435 cancer cell lines | |
| PubChem ID | 44448243 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:473275-1 | |
| Safety | NA |