Phytochemical Name : (S)-sativan

Properties Information
PhytoCAT-ID PhytoCAT-1536
Phytochemical name or plant extracts (S)-sativan
PMID 31487934
Literature evidence In this study, four novel isoflavanes (1-3 and 5) and four known analogues (4 and 6-8) were isolated from an ethanolic extract of the rattans of S. suberectus.
IUPAC name 3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-ol
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Spatholobus suberectus
Geographical availability Assam, China South-Central, China Southeast, East Himalaya, Laos, Thailand, Vietnam
Plant parts Raatan
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 60.1 ± 7.4 µM against MCF-7 34.1 ± 6.3 µM against MDA-MB-231
Potency NA
Cell line/ mice model MCF-7, MDA-MB-231
Additional information  2. Shows selective cytotoxicity against MDA-MB-231 cells
PubChem ID 596401
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:519185-1
Safety NA