| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1942 | |
| Phytochemical name or plant extracts | (E)-resveratrol 3-O-rutinoside | |
| PMID | 30346066 | |
| Literature evidence | In addition, compounds 1-3 showed low toxicity against normal human prostate cell line, with selectivity indices greater than five across the carcinoma cells, indicating that the compounds possess potential in the development of low-toxicity chemotherapeutic agents. | |
| IUPAC name | (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-({[(1R,2R,3R,4S,5R)-2,3,4-trihydroxy-5-methylcyclohexyl]oxy}methyl)oxane-3,4,5-triol | |
| Phytochemicals’ class or type of plant extracts | Resveratrol derivative | |
| Source of phytochemicals or plant Extracts | Commiphora africana | |
| Geographical availability | Angola, Benin, Botswana, Burkina, Cameroon, Caprivi Strip, Chad, Djibouti, Eritrea, Ethiopia, Gambia, Ghana, Ivory Coast, Kenya, KwaZulu-Natal, Malawi, Mali, Mauritania, Mozambique, Namibia, Niger, Nigeria, Northern Provinces, Rwanda, Senegal, Somalia, Sudan, Swaziland, Tanzania, Togo, Uganda, Zambia, Zaïre, Zimbabwe | |
| Plant parts | Stem | |
| Other cancers | NA | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 16.80 μM against MCF7 | |
| Potency | Displayed the highest antiproliferative effect on the cell lines, with IC50 values of 16.80, 21.74, 17.89, and 17.44 μM, against MCF7, A549, PC3, and HepG2 human cancer cell lines, respectively. | |
| Cell line/ mice model | MCF-7, A549, PC3, and HepG2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:127576-1 | |
| Safety | compounds 1-3 showed low toxicity against normal human prostate cell line, with selectivity indices greater than five across the carcinoma cells, indicating that the compounds possess potential in the development of low-toxicity chemotherapeutic agents. |