Phytochemical Name : (3S)-7-hydroxy-8,2′-dimethoxy-4′,5′-methylenedioxyisoflavane

Properties Information
PhytoCAT-ID PhytoCAT-1535
Phytochemical name or plant extracts (3S)-7-hydroxy-8,2′-dimethoxy-4′,5′-methylenedioxyisoflavane
PMID 31487934
Literature evidence In this study, four novel isoflavanes (1-3 and 5) and four known analogues (4 and 6-8) were isolated from an ethanolic extract of the rattans of S. suberectus.
IUPAC name (3S)-3-{4,5-bis[(1-hydroxyethenyl)oxy]-2-methoxyphenyl}-8-methoxy-3,4-dihydro-2H-1-benzopyran-7-ol
Phytochemicals’ class or type of plant extracts Isoflavane
Source of phytochemicals or plant Extracts Spatholobus suberectus
Geographical availability Assam, China South-Central, China Southeast, East Himalaya, Laos, Thailand, Vietnam
Plant parts Raatan
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 93.6 ± 17.3 µM against MCF-7 >100µM against MDA-MB-231
Potency NA
Cell line/ mice model MCF-7, MDA-MB-231
Additional information  Inhibits the proliferation of MCF-7 cells
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:519185-1
Safety NA