Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1535 | |
Phytochemical name or plant extracts | (3S)-7-hydroxy-8,2′-dimethoxy-4′,5′-methylenedioxyisoflavane | |
PMID | 31487934 | |
Literature evidence | In this study, four novel isoflavanes (1-3 and 5) and four known analogues (4 and 6-8) were isolated from an ethanolic extract of the rattans of S. suberectus. | |
IUPAC name | (3S)-3-{4,5-bis[(1-hydroxyethenyl)oxy]-2-methoxyphenyl}-8-methoxy-3,4-dihydro-2H-1-benzopyran-7-ol | |
Phytochemicals’ class or type of plant extracts | Isoflavane | |
Source of phytochemicals or plant Extracts | Spatholobus suberectus | |
Geographical availability | Assam, China South-Central, China Southeast, East Himalaya, Laos, Thailand, Vietnam | |
Plant parts | Raatan | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 93.6 ± 17.3 µM against MCF-7 >100µM against MDA-MB-231 | |
Potency | NA | |
Cell line/ mice model | MCF-7, MDA-MB-231 | |
Additional information | Inhibits the proliferation of MCF-7 cells | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:519185-1 | |
Safety | NA |