| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-420 | |
| Phytochemical name or plant extracts | (-)-kunstleramide | |
| PMID | 30108756 | |
| Literature evidence | Some of the piperazine derivatives (17-22) strongly inhibit the growth of breast cancer cells with IC50 values of 8-20 ?M. | |
| IUPAC name | (2E,4E,6R)-7-(3,4-dimethoxyphenyl)-N-ethyl-6-hydroxyhepta-2,4-dienamide | |
| Phytochemicals’ class or type of plant extracts | Unsaturated amide | |
| Source of phytochemicals or plant Extracts | Beilschmiedia kunstleri | |
| Geographical availability | Borneo, Laos, Malaya, Sumatera, Thailand | |
| Plant parts | Bark | |
| Other cancers | Breast cancer, Lung cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 12.87 ± 0.71 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | A-549, Hela, MCF-7, IMR-32 | |
| Additional information | NA | |
| PubChem ID | 72196849 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:462817-1 | |
| Safety | NA |