| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-612 | |
| Phytochemical name or plant extracts | (-)-5,6-dihydro-6-undecyl-2H-pyran-2-one | |
| PMID | 23738449 | |
| Literature evidence | In vitro assay of compounds 2 and 3 demonstrated moderate cytotoxic activities against human prostate (PC-3), colon (HCT-116) and breast (MCF-7) cancer cells, while the chloroform and ethyl acetate fractions of H. superba were found to exhibit moderate AChE inhibitory activity (IC50 72 and 60 microg/mL). | |
| IUPAC name | 2-undecyl-2,3-dihydropyran-6-one | |
| Phytochemicals’ class or type of plant extracts | Lactone | |
| Source of phytochemicals or plant Extracts | Horsfieldia superba | |
| Geographical availability | Malaya, Sumatera | |
| Plant parts | Stem bark | |
| Other cancers | Breast cancer, Colon cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | In vitro assay of compounds 2 and 3 demonstrated moderate cytotoxic activities against human prostate (PC-3), colon (HCT-116) and breast (MCF-7) cancer cells, while the chloroform and ethyl acetate fractions of H. superba were found to exhibit moderate AChE inhibitory activity (IC50 72 and 60 μg/mL). | |
| Cell line/ mice model | PC-3, HCT-116, MCF-7 | |
| Additional information | NA | |
| PubChem ID | 10923030 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:585787-1#synonyms | |
| Safety | NA |