Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1102 | |
Phytochemical name or plant extracts | (+)-lariciresinol | |
PMID | 18656934 | |
Literature evidence | Dihydroconiferyl alcohol, (+)-lariciresinol, (+)-pinoresinol, (+)-syringaresinol, and protocatechuic acid methyl ester exhibited cytoprotective activity in cultured MCF-7 cells stressed by H2O2. | |
IUPAC name | 4-[[(3R,4R,5S)-5-(4-hydroxy-3-methoxyphenyl)-4-(hydroxymethyl)oxolan-3-yl]methyl]-2-methoxyphenol | |
Phytochemicals’ class or type of plant extracts | Lignan | |
Source of phytochemicals or plant Extracts | Euterpe oleracea | |
Geographical availability | Brazil North, Brazil Northeast, Colombia, Ecuador, French Guiana, Guyana, Suriname, Trinidad-Tobago, Venezuela | |
Plant parts | Fruits | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | DPPH and Hydroxyl Radical Scavenging Activities 22.4 ± 3.0 μg/mL and 0.70 ± 0.13 μg/mL respectively. | |
Potency | The reductions in risk of breast cancer and invasive cancer were explained primarily by higher intakes of lariciresinol and pinoresinol in premenopausal women and of lariciresinol and matairesinol in postmenopausal women | |
Cell line/ mice model | MCF-7 | |
Additional information | NA | |
PubChem ID | 332427 | |
Additional PMIDs | 17374837 18647433 22113872 21943063 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:666941-1 | |
Safety | NA |