| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1622 | |
| Phytochemical name or plant extracts | (+)-Torreyol | |
| PMID | 28606152 | |
| Literature evidence | CONCLUSIONS: This demonstrates that yeast-based genome mining, guided by transcriptomics, is a promising approach for uncovering bioactive compounds from medicinal mushrooms. | |
| IUPAC name | (1S,4R,4aS,8aR)-1,6-dimethyl-4-propan-2-yl-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-ol | |
| Phytochemicals’ class or type of plant extracts | Sesquiterpenoid | |
| Source of phytochemicals or plant Extracts | Lignosus rhinocerotis | |
| Geographical availability | NA | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 3.5 ± 0.58 μg/mL against MCF-7 | |
| Potency | (+)-Torreyol and α-cadinol were tested against a panel of human cancer cell lines and the latter was found to exhibit selective potent cytotoxicity in breast adenocarcinoma cells (MCF7) with IC50 value of 3.5 ± 0.58 μg/ml while α-cadinol is less active (IC50 = 18.0 ± 3.27 μg/ml). | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | 11990360 | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |