| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1470 | |
| Phytochemical name or plant extracts | Hederagenin 3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside | |
| PMID | 29189079 | |
| Literature evidence | Only the monodesmosidic saponin with a free carboxyl group at C-28 (12) exhibited significant cytotoxicities against HepG2, MCF-7 and A-549 cell lines with the IC50 values of 8.98 ± 0.19, 12.48 ± 0.45 and 11.62 ± 0.54 μM, respectively. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid saponin | |
| Source of phytochemicals or plant Extracts | Lonicera similis Hemsl | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Myanmar | |
| Plant parts | Buds | |
| Other cancers | Breast cancer, Lung cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 12.48 ± 0.45 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | HepG2, MCF-7, A-549 | |
| Additional information | Exhibits cytotoxicity against HepG2, MCF-7 and A-549 cell lines, induces HepG2 and A-549 cells apoptosis significantly | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:149094-1 | |
| Safety | NA |