| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1965 | |
| Phytochemical name or plant extracts | 4-[(R)-1, 3-benzodioxol-5-ylhydroxymethyl]-3-(1, 3-benzodioxol-5-ylmethyl)dihydro-, (3S, 4R)-2(3H)-furanone | |
| PMID | 28839377 | |
| Literature evidence | SUMMARY: The chemical investigation of the stems of W. scytophylla resulted in the isolation of 12 compoundsThe 12 compounds including six lignans (7-12), in which compound 8 was a new natural productThe isolated compounds 1 and 7-12 were evaluated for their antitumor activitiesThe chemotaxonomic significance of all the isolations was summarized. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Lignan | |
| Source of phytochemicals or plant Extracts | Wikstroemia scytophylla | |
| Geographical availability | China South-Central, Tibet | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Lung cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | >40 μM against MCF-7 | |
| Potency | Compounds 1 and 7-12 exhibited weak antitumor activities (IC50>40 μM). Compound 8 is 4-[(R)-1, 3-benzodioxol-5-ylhydroxymethyl]-3-(1, 3-benzodioxol-5-ylmethyl)dihydro-, (3S, 4R)-2(3H)-furanone | |
| Cell line/ mice model | HL-60, SMMC-7721, A549, MCF-7, and SW480 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:833183-1 | |
| Safety | NA |